Nintendo’s Wii U: First Impressions
















GamePad


The Wii U GamePad has a 6.2-inch touchscreen.


Click here to view this gallery.













[More from Mashable: Meet the Super Fan Who Waited in Line for a Month for a Wii U [VIDEO]]


Nintendo‘s newest console has only been available for one day, but that’s still enough time for early-bird consumers to get their hands on the Wii U, and test out its features and games.


We spent the last 24 hours playing with the Wii U, and have organized our early thoughts on the system. Read on if you’re on the fence about buying one.


[More from Mashable: Toys ‘R’ Us Says Wii U Pre-Order Shipments May Be Delayed]


Out of the Box


Setting up the Wii U is easy, but installing the software is more of a process. Nintendo issued a day-one patch to activate features such as MiiVerse, the company’s social features; this means users will spend between one to three hours (depending on connection speed) downloading and installing a patch that bricks their system. Not a great way to greet consumers excited to play your games. But there’s a chance that servers won’t be as busy in the coming weeks, so download times may improve. Each game I inserted had its own patch too, which users have to install on the second playthrough.


After getting through the patch, user still face an involved setup. They have to create their Mii avatar before they start playing, and create a Nintendo Network ID for network play. Users must also set up the GamePad’s universal remote functionality, which is thankfully the easiest part of the process. They only have to pick their TV manufacturer (the Wii U knows what to do next). The GamePad controls volume, input source and channels.


Look and Feel


The GamePad is the Wii U’s main portal, so users need it to access all the relevant menus (the console shows a different menu from the television); here, users can launch applications by touch. The default view includes apps such as Netflix, Hulu Plus, Amazon Video Services and YouTube; but only Netflix is available now, which seems a bit like false advertising. Loading other options, such as the Nintendo eShop, requires pressing the Home button on the controller, which is unintuitive at first. But soon, the button quickly becomes a handy way to navigate to other parts of the Wii U, like the upcoming Nintendo TVii.


The most troublesome thing about the console is that everything moved slowly; launching games and apps took a long time. I felt like I spent awhile looking at a spinning blue circle.


Wii U games definitely take advantage of the console’s ability to support high-definition graphics. Cartoony games, such as Scribblenauts Unlimited or Nintendo Land look beautiful. For games such as ZombiU, which are supposed to appear more realistic, users might be disappointed. This system is supposed to be the next-generation of gaming consoles — meant to outshine the Xbox 360 — but I can’t say it achieves that.


The GamePad


Pre-launch, Nintendo has spent much of its time crowing about the features of the GamePad, a hybrid touch screen and controller that’s central to the Wii U. The first thing I noticed is its large size; but after spending a few hours with the GamePad, I’ve concluded that it won’t weigh you down like an iPad, yet is substantial enough that it doesn’t feel like a toy (though the glossy finish makes it look like one.)


Unfortunately, the GamePad takes some getting used to as an actual controller, especially for games that require more than simple controls or the gyroscope. My biggest complaint is that Nintendo bucked all gaming-controller tradition by swapping the position of the right analog stick and the four letter buttons. Anyone who has played any other modern console (including Nintendo’s own GameCube) knows instinctively that the analog stick goes below the buttons; but Nintendo flipped them on both the GamePad and the Pro Controller. If the company is only targeting non-gamers, they won’t notice; but this will be a difficult change for many others. Despite this drawback, the buttons, and especially triggers, feel good.


The GamePad is mostly dominated by the 6.2-inch touch screen with a passable resolution: 854 x 480. The most appealing feature of the Wii U — that users can play games or watch movies entirely on the GamePad — may be spoiled for some looking for HD crispness. Still, I watched a whole episode of Portlandia from Netflix on the GamePad, and also spent time playing New Super Mario Bros. U with the television off. Being able to isolate your gameplay to a smaller screen is very novel, and one of my favorite parts of the system.


Games


Nintendo’s Wii U has a better launch lineup coming out, compared to other consoles — but only a few titles stick out. Almost everyone I talked to in line at the Nintendo World store during the Wii U launch wanted New Super Mario Bros. U or ZombiU, both of which are fun titles. Nintendo Land, which is a pack-in if users purchase the Deluxe model, is going to be a huge hit at parties; from what I’ve seen so far, it has some engrossing minigames. I haven’t cracked open Scribblenauts Unlimited yet, but in demos it looks like a very promising title that would go well with a touch screen.


Some non-exclusive titles on other consoles are also appealing. I’m looking forward to digging in to Epic Mickey 2 and Tekken Tag Tournament 2. While the system had 24 launch titles, many more are expected to debut in the coming months.


I plan to spend Thanksgiving week exploring the Wii U, and will write a more detailed report on whether it’s the right console for gamers, families or casual users.


This story originally published on Mashable here.


Gaming News Headlines – Yahoo! News



Read More..

Jenna von Oy Blogs: The Importance of Mommy Me-Time

Celebrity blogger Jenna von Oy is a new mama!


Best known for her roles as Six on Blossom and Stevie on The Parkers, von Oy is also a musician who has released two albums and is set to publish a book, The Betweeners.


von Oy, 35, wed Brad Bratcher on Oct. 10, 2010, and resides in Nashville with her husband and five dogs.


They welcomed their first child, daughter Gray Audrey, on May 21. She is now almost 6 months old.


In her latest blog, von Oy reflects on the important of taking time for yourself.


You can find her on Facebook and Twitter @JennavonOy, as well as posting on her weekly blog, The Cradle Chronicles.


Jenna von Oy's Blog: The Importance of Mommy Me-Time
Gray and I – attached at the hip! – Courtesy Jenna von Oy



Any mom who tells you she absolutely never has alone time is either lying or damn-near ready to be fitted for her straightjacket! I must admit it is getting increasingly more difficult to find time for myself in the midst of the madness. Now that Gray is almost six months old, it seems as though her naptime is getting shorter and shorter with each day that passes. Consequently, it is difficult to attend to my daily “chores.”


There are mornings I long for a shower so badly that I could wail my way through an entire box of tissue, though I concede it might be better spent cleaning off the drool and snot. And while I’m certain the lingering Eau de Spit-up is attractive all on its own, some days I simply look in the mirror, huff audibly, and decide a combination of deodorant and perfume will just have to do.


It’s the perfect accompaniment to my sweatpants, T-shirt, and un-brushed hair, I suppose. (I might have refrained from admitting all of that aloud, if I didn’t suspect many of you could say the same!)


We’ve all seen the candid photographs of celebrities out shopping with their kids, nursing a latte in one hand while pushing a stroller with the other. I am befuddled by the folks who manage to look eternally composed during those outings! Apparently, I am not a card-carrying member of the calm, cool and collected club. I’m thankful the paparazzi aren’t as prevalent here in Nashville, as I undoubtedly wouldn’t fair as well.


But it’s the life of a mother, isn’t it? It’s wonderful and, simultaneously, dirty work. And it’s no secret that I love it, despite my current inability to remain clean for longer than two consecutive minutes. If showering is so abysmally tough to conjure up the time for, exercising the right to have some “mommy me-time” is as farfetched as a cow jumping over the moon. (Or anything jumping over the moon, for that matter…)


But it’s an absolute necessity — for all of us! None of us is exempt from the urge to take a few moments to regroup. Warning: our sanity may be at stake if we don’t!


I know, I know, “me-time” sounds like a miracle, to say the least … something akin to winning the lottery twice or seeing the Virgin Mary on a loaf of Wonder bread. If shaving my legs has become a thing of the past, you ask, how can I possibly find time to do something relaxing such as curling up with a good novel or sipping tea in front of the bay window? The simple (but, as you know, not so simple at all) answer is: you make time. For your sake and the sake of your children!


I certainly don’t purport to be mother-of-the-year, nor am I an authority on the subject; I just know my own innate thirst for serenity. It’s imperative. Consider it this way: a car requires gas or it risks stalling in the middle of a busy intersection, right? Without refueling, I find myself doing much the same thing. My frustration levels peak and I fear I can’t be an effective parent.


Mind you, I’m painfully aware that this is easier said than done. Like most of you out there, I don’t have a nanny or easily found babysitters. My parents and in-laws don’t live close enough to stop by at a moment’s notice so they can take care of Gray while I “luxuriate.” Not to mention, separation anxiety has begun to rear its ugly head lately — for both Gray and I. I barely have enough time to get my work done, much less rest!


I am my child’s full-time guardian, so my time is devoted to her … and I wouldn’t have it any other way. Having the ability to spend each day with Gray is something I feel both blessed and passionate about. But everyone has a desire for some time to themselves, including yours truly, and I expect that the future will prove it harder and harder to come by.


How would you bide your time if you had one hour a day to do anything you wish? Forget laundry, or sweeping the floor, or feeding the dogs, or eating lunch. Those are all necessities. I’m referring to one solid hour for something that makes you take a deep breath and unwind.


Jenna von Oy's Blog: The Importance of Mommy Me-Time
Writing my blog – Courtesy Jenna von Oy


If I had my druthers, I might spend my me-time sipping a gorgeous glass of Chateau Margaux and whipping up a Cassoulet. Cooking is my therapy, so I’d chop and mince to my heart’s content! I might light some candles and draw a bubble bath, hit up the vintage stores, pen a new song, or work on editing my book for publication (which, sadly, I’ve been neglecting for months now). I might even knit a shawl or begin a photography project.


It all sounds dreamy but, alas, I know none of those things are in the cards any time soon. Don’t get me wrong — my husband is amazing at taking care of our little one for a while in the evenings so I can get a few things accomplished — but lo’ and behold, that obligatory shower generally wins out in the election process! I imagine you can sympathize.


And I don’t want to ignore the fact that my husband should have some downtime as well. He gets up at 5:00 every morning and works until 5:00 in the evening. Daddies need quiet time too! Sometimes, to take the edge off, we try to combine household projects with activities we enjoy.


For instance, Brad often fires up his iPod with a favorite music list and mows the lawn. Combining the outdoors with tunes and physical labor makes him zone out blissfully. Other times, he irons while watching political discourse on his computer. Of course, I can’t swear this relaxes him, per se. I’m often surprised his work shirts don’t have holes burned into them in the shape of certain outspoken, ostentatious commentators. That said, at least he’s found a way to enjoy the mundane task at hand.


My mom recently flew in to visit us for two weeks and I can’t express how grateful I was for her assistance. She offered that my husband and I take advantage of her presence by doing a few things for ourselves. As heartbreaking as it was to leave our daughter for an hour or two, we took her up on it and went on a beautiful dinner date.


I also got to do something special that I’ve been hungering for … I had a massage!!!! I’d set aside some money I received for my birthday in May, and swore I’d eventually get around to using it for that purpose alone. Talk about quality “me-time!” I almost wept with relief as the massage therapist worked my shoulders and back. Breastfeeding definitely takes its toll! It was an incredible blessing to enjoy such an extravagance, and I can’t thank my mom enough for making it possible.


It has been a bit of a struggle, but I’m learning to appreciate and accept the help that is offered to me. I want to be Supermom, but I know sometimes that means allocating some time to concentrate on my own peace of mind. I’m often too quick to turn down proposals of assistance, because I fret about taking advantage of friends or family. I worry it means I “can’t handle” my own life. But that’s probably just my ego talking.


Hearing about a growing number of women with postpartum depression makes me recognize my own demand for quietude. Reserving personal time for my needs is crucial for my health and helps to cut down on my stress level. This means I can be a better mother to my daughter and a more supportive wife to my husband.


I’m not even remotely claiming to be a doctor, but I imagine most of them would be avid proponents of mommy me-time … even when it is tough to come by. Sometimes I think the most selfless thing you can do is concentrate on yourself for a few minutes. It may seem counterintuitive, but it allows you to attack the day with a sense of calm. I can certainly speak to that. I know I’m a more confident and even-keeled parent when I have a few minutes to recharge my emotional batteries!


In a way, contributing to this blog (as well as my weekly blog, The Cradle Chronicles) has become an integral part of my me-time maintenance. I covet the moments I am able to devote to purging my thoughts onto paper. If you’re wondering why my posts are typically so long-winded, there’s your answer! I long for the moments spent furiously typing away on my laptop. This has become a comforting creative outlet that I treasure, and I appreciate you being a part of it with me.


Jenna von Oy's Blog: The Importance of Mommy Me-Time
Reading with Ruby – Courtesy Jenna von Oy


Wishing you all a few moments of blissful respite this week…


Until next time,


– Jenna von Oy


More from Jenna’s PEOPLE.com blog series:


Read More..

EU drug regulator OKs Novartis' meningitis B shot

LONDON (AP) — Europe's top drug regulator has recommended approval for the first vaccine against meningitis B, made by Novartis AG.

There are five types of bacterial meningitis. While vaccines exist to protect against the other four, none has previously been licensed for type B meningitis. In Europe, type B is the most common, causing 3,000 to 5,000 cases every year.

Meningitis mainly affects infants and children. It kills about 8 percent of patients and leaves others with lifelong consequences such as brain damage.

In a statement on Friday, Andrin Oswald of Novartis said he is "proud of the major advance" the company has made in developing its vaccine Bexsero. It is aimed at children over two months of age, and Novartis is hoping countries will include the shot among the routine ones for childhood diseases such as measles.

Novartis said the immunization has had side effects such as fever and redness at the injection site.

Recommendations from the European Medicines Agency are usually adopted by the European Commission. Novartis also is seeking to test the vaccine in the U.S.

Read More..

Wall Street rallies further on budget talk hopes

Robert Pattinson and Kristen Stewart are coming to the end of their whirlwind international promotional tour for "The Twilight Saga: Breaking Dawn - Part 2," and while the on-screen couple have yet to confirm they've reunited off-screen, they appear to be enjoying each other's company. Following the final "Twilight" film's Germany premiere in Berlin on Friday, Robert, 26, and Kristen, 22, were photographed heading to the Berolina Bowling Lounge to relax after their completing their red carpet duties.
Read More..

Israel says prefers diplomacy but ready to invade Gaza

GAZA/JERUSALEM (Reuters) - Israel bombed dozens of targets in the Gaza Strip on Monday and said that while it was prepared to step up its offensive by sending in troops, it preferred a diplomatic solution that would end Palestinian rocket fire.


Mediator Egypt said a deal for a truce to end the fighting could be close. The leader of Hamas said it was up to Israel to end the new conflict it had started. Israel says its strikes are to halt Palestinian rocket attacks.


U.N. Secretary-General Ban Ki-moon, touring the region in hopes of helping broker a peace arrived in Cairo, where he met Egypt's foreign minister in preparation for talks with the new, Islamist president, Mohamed Mursi, on Tuesday. He also plans to meet Israeli Prime Minister Benjamin Netanyahu in Jerusalem.


Israeli attacks on the sixth day of fighting raised the number of Palestinian dead to 101, the Hamas-run Health Ministry said, listing 24 children among them. Hospital officials in Gaza said more than half of those killed were non-combatants. Three Israeli civilians died on Thursday in a rocket strike.


Militants in the Gaza Strip fired 110 rockets at southern Israel on Monday, causing no casualties, police said.


For the second straight day, Israeli missiles blasted a tower block in the city of Gaza housing international media. Two people were killed there, one of them an Islamic Jihad militant.


Khaled Meshaal, exiled leader of Hamas, said a truce was possible but the Islamist group, in charge of the Gaza Strip since 2007, would not accept Israeli demands and wanted Israel to halt its strikes first and lift its blockade of the enclave.


"Whoever started the war must end it," he told a news conference in Cairo, adding that Netanyahu, who faces an election in January, had asked for a truce, an assertion a senior Israeli official described as untrue.


Meshaal said Netanyahu feared the domestic consequences of a "land war" of the kind Israel launched four years ago: "He can do it, but he knows that it will not be a picnic and that it could be his political death and cost him the elections."


For Israel, Vice Prime Minister Moshe Yaalon has said that "if there is quiet in the south and no rockets and missiles are fired at Israel's citizens, nor terrorist attacks engineered from the Gaza Strip, we will not attack."


Yaalon also said Israel wanted an end to Gaza guerrilla activity in the neighboring Egyptian Sinai peninsula.


Although 84 percent of Israelis supported the current Gaza assault, according to a poll by Israel's Haaretz newspaper, only 30 percent wanted an invasion, while 19 percent wanted their government to work on securing a truce soon.


DIPLOMACY "PREFERRED"


"Israel is prepared and has taken steps, and is ready for a ground incursion which will deal severely with the Hamas military machine," a senior official close to Netanyahu told Reuters.


"We would prefer to see a diplomatic solution that would guarantee the peace for Israel's population in the south. If that is possible, then a ground operation would no longer be required. If diplomacy fails, we may well have no alternative but to send in ground forces," he added.


Egypt, where Mursi has his roots in the Muslim Brotherhood seen as mentors to Hamas, is acting as a mediator in the biggest test yet of Cairo's 1979 peace treaty with Israel since the fall of Hosni Mubarak.


"I think we are close, but the nature of this kind of negotiation, (means) it is very difficult to predict," Egyptian Prime Minister Hisham Kandil, who visited Gaza on Friday in a show of support for its people, said in an interview in Cairo for the Reuters Middle East Investment Summit.


Egypt has been hosting leaders of both Hamas and Islamic Jihad, a smaller armed faction.


Israeli media said a delegation from Israel had also been to Cairo for truce talks. A spokesman for Netanyahu's government declined comment on the matter.


Egypt's foreign minister, who met U.N. chief Ban on Monday, is expected to visit Gaza on Tuesday with a delegation of Arab ministers.


THOUSANDS MOURN FAMILY


Thousands turned out on Gaza's streets to mourn four children and five women, among 11 people killed in an Israeli strike that flattened a three-storey home the previous day.


The bodies were wrapped in Palestinian and Hamas flags. Echoes of explosions mixed with cries of grief and defiant chants of "God is greatest".


The deaths of the 11 in an air strike drew more international calls for an end to six days of hostilities and could test Western support for an offensive Israel billed as self-defense after years of cross-border rocket attacks.


Israel said it was investigating its air strike that brought the home crashing down on the al-Dalu family, where the dead spanned four generations. Some Israeli newspapers said the wrong house may have been mistakenly targeted.


In scenes recalling Israel's 2008-2009 winter invasion of the coastal enclave, tanks, artillery and infantry have massed in field encampments along the sandy, fenced-off border and military convoys moved on roads in the area.


Israel has also authorized the call-up of 75,000 military reservists, so far mobilizing around half that number.


The Gaza fighting adds to worries of world powers watching an already combustible region, where several Arab autocrats have been toppled in popular revolts for the past two years and a civil war in Syria threatens to spread beyond its borders.


In the absence of any prospect of permanent peace between Israel and Islamist factions such as Hamas, mediated deals for each to hold fire unilaterally have been the only formula for stemming bloodshed in the past.


Israel's declared goal is to deplete Gaza arsenals and force Hamas to stop rocket fire that has hit Israeli border towns for years.


Hamas and other groups in Gaza are sworn enemies of the Jewish state which they refuse to recognize and seek to eradicate, claiming all Israeli territory as rightfully theirs.


Hamas won legislative elections in the Palestinian Territories in 2006. A year later, after the collapse of a unity government under President Mahmoud Abbas, the Islamist group seized Gaza in a brief civil war with Abbas's forces.


(Writing by Jeffrey Heller, Dan Williams and Peter Graff; Editing by Alastair Macdonald)

Read More..

Who Are the ‘Anti-Israel’ Press Behind Rupert Murdoch’s Twitter Attack?
















Rupert Murdoch can apologize (as he sort of did) about his “Jewish-owned press” tweet, but he still can’t take it back. And because that tweet is out there, the big question now—after “Why is he still on there?” and “Wow, that’s really offensive, right?”—is which press, exactly, he was referring to. Here’s the tweet that Murdoch sent out on Saturday night: 



Why Is Jewish owned press so consistently anti- Israel in every crisis?













— Rupert Murdoch(@rupertmurdoch) November 18, 2012


After an avalanche of Twitter blowback, Murdoch soon faux-apologized…



“,Jewish owned press” have been sternly criticised, suggesting link to Jewish reporters.Don’t see this, but apologise unreservedly.


— Rupert Murdoch(@rupertmurdoch) November 18, 2012


…”don’t see this” being Murdochian for faux-apology.


RELATED: Rupert Murdoch Brightens Every Newsroom He Enters


As the initial round of shock wears off (The Daily Beast’s Peter Beinart eloquently wrote about how stupid and offensive this tweet was), journalists and editors are now actually trying to make some kind of sense of which outlet or outlets Murdoch may have gotten all drunk-uncle-at-Thanksgiving over. So, with the help of journalists on the case, here’s our best attempt at “Murdoch Whispering“: 


RELATED: How U.K. Tabloids Are Getting Around Prince Harry’s Nudity Warning


He Is Talking About The New York Times Foreign Policy’s Blake Hounshell put it succinctly: 



FWIW Murdoch was probably referring to the NYT with that weird tweet.


— Blake Hounshell (@blakehounshell) November 18, 2012


And it was shared be Buzzfeed’s Ben Smith:



Wolff also assumes, as I did, that Murdoch’s Jewish-owned press meant the Times guardian.co.uk/commentisfree/…


— Ben Smith (@BuzzFeedBen) November 19, 2012


The reason Smith, Hounshell, and The Guardian‘s Michael Wolff all think it’s a Times-centered attack isn’t just because of an anti-Semitic slam against the Sulzbergers (more on this in a tiny bit) but because of Murdoch’s various “wars” and his rivalry with The New York Times. Back in 2010, as Vanity Fair pointed out, Murdoch was warring with executive editor Bill Keller, and he was seen tweeting dissing the well-liked Times‘s public editor, Margaret Sullivan, not too long ago: 



Amusing fuss over NYT public editor.We see all two million daily subscribers as our very public editors.


— Rupert Murdoch(@rupertmurdoch) November 8, 2012


So maybe this tweet was another pot shot, albeit with more anti-Semitic tone. But as Wolff points out, being Jewish-owned doesn’t even apply to The Times anymore, which kinda makes it even more anti-Semitic if he was just going by the Sulzberger surname:



To describe the Times this way is both quizzical, and we can assume, pointed. Because, as it happens, the Times isn’t, per se, “Jewish”. True, the Sulzbergers, who control the company, were once a prominent Jewish family. But the Times’ chairman and publisher, Arthur Sulzberger, is half-Jewish (on his father’s side) and was raised as an Episcopalian. Murdoch knows this full well. So what he is saying is something more like “Jewish-tainted press”, which, all in all, seems more, not less, antisemitic.



He Was Talking About CNN and the AP If you go to the New York Times report on the whole thing that might be referring to The Times, they point to CNN and the AP. “In an earlier message he had said, “CNN and AP bias to point of embarrassment,” writes The Times‘s Amy Chozick.


RELATED: New York Times Devours Gothamist


He Was Channeling Wendi’s Broken English and Trolling His ‘Minders’ “Curiously, Murdoch’s wife Wendi often uses the word ‘Jewish’in an atonal context – ‘You Jewish, right? I know you Jewish!’– that makes Murdoch’s minders jump.  He may even become more retrograde to bedevil his minders.” wrote Wolff. Based on a life experience which includes very blunt Asian relatives and a large extended family, there is a definite possibility that Wendi might not know how harsh  ”You Jewish, right?” comes off. It’s hard to say the same for Rupert.


RELATED: The Vatican Gets Trendy: Puts Newspaper Online, Plans a Paywall


He Wasn’t Talking About Mother Jones‘s Adam Weinstein: 



*I* don’t own any media. You laid me off in 2008. RT @rupertmurdoch: Why Is Jewish owned press so consistently anti-Israel in every crisis?


— Adam Weinstein (@AdamWeinstein) November 18, 2012


Social Media News Headlines – Yahoo! News



Read More..

Jessica Simpson Shows Off 60-Lb. Weight Loss















11/18/2012 at 03:30 PM EST



Hot mamma alert!

Just more than six months after welcoming daughter Maxwell Drew on May 1 with fiancé Eric Johnson, Jessica Simpson has lost more than 60 lbs. – and she doesn't need to wear anything more revealing than a pair of boot-cut jeans to prove it.

Dressed down in denim and a hot pink blazer, the new mom, 32, showed off her slim figure Saturday at a Tampa, Fla., event for her fashion line, the Jessica Simpson Collection. Two days prior, the Weight Watchers spokesperson posted a sneak peek on Twitter of the commercial she shot for the weight-loss company.

For Simpson, getting back into shape after giving birth hasn't been as easy as whipping up her favorite pregnancy craving, macaroni and cheese.

"My body is not bouncing back like a supermodel," she said in September, the same month she first debuted her post-baby body. "I'm just your everyday woman who is trying to feel good and be healthy for her daughter, her fiancé and herself."

Read More..

EU drug regulator OKs Novartis' meningitis B shot

LONDON (AP) — Europe's top drug regulator has recommended approval for the first vaccine against meningitis B, made by Novartis AG.

There are five types of bacterial meningitis. While vaccines exist to protect against the other four, none has previously been licensed for type B meningitis. In Europe, type B is the most common, causing 3,000 to 5,000 cases every year.

Meningitis mainly affects infants and children. It kills about 8 percent of patients and leaves others with lifelong consequences such as brain damage.

In a statement on Friday, Andrin Oswald of Novartis said he is "proud of the major advance" the company has made in developing its vaccine Bexsero. It is aimed at children over two months of age, and Novartis is hoping countries will include the shot among the routine ones for childhood diseases such as measles.

Novartis said the immunization has had side effects such as fever and redness at the injection site.

Recommendations from the European Medicines Agency are usually adopted by the European Commission. Novartis also is seeking to test the vaccine in the U.S.

Read More..

Wall Street Week Ahead: Going off "cliff" with a bungee cord

NEW YORK (Reuters) - The 1987 crash. The Y2K bug. The debt ceiling debacle of 2011.


All these events, in the end, turned out to be buying opportunities for stocks. So will the "fiscal cliff," some investors say as they watch favorite stocks tumble during the political give-and-take happening in Washington.


The first round of talks aimed at avoiding the "fiscal cliff" caused a temporary rise in equities on Friday, signaling Wall Street's recent declines could be a buying opportunity. The gains were small and sentiment remains weak, but it suggests hope for market bulls.


Though shares ended moderately higher on Friday, it was not enough to offset losses for the week. The S&P was down 1.5 percent, while both the Dow and the Nasdaq fell 1.8 percent.


The S&P 500 is down more than 5 percent in the seven sessions that followed President Barack Obama's re-election. Uncertainty arose as attention turned to Washington's task of dealing with mandated tax hikes and spending cuts that could take the U.S. economy back into recession.


Some see the market's move as an overreaction to hyperbolic headlines about policy gridlock in Washington, believing stocks may start to rebound in what should be a quiet few days ahead of the Thanksgiving holiday next Thursday.


"It just doesn't seem to make any sense that you suddenly wake up the day after the election and realize we've got a fiscal cliff," said Krishna Kumar, partner at New York hedge fund Goose Hollow Alpha Advisors.


Not long ago the S&P was on target for its second-best year in the last 10, riding a 17 percent advance in 2012. That's been halved to about 8 percent, which isn't bad but disappointing compared with just a month ago.


Investors have been selling the year's winners. Apple is down 25 percent from its peak above $700. General Electric is down 14 percent; Google has lost 16 percent. Overall, the stocks that make up the top 10 percent of performers in the month prior to Election Day have been the worst performers since, according to Bespoke Investment Group of Harrison, New York.


"I think it's a good opportunity to be long stocks at these levels," said Kumar.


Hikes on capital gains and dividend taxes are on the line, and Obama has dug in his heels on what he sees as a mandate to make the tax code more progressive.


He seems to have the upper hand in dealings with Congress because Republican lawmakers don't want to see tax rates increase, which is what will happen if no solution is found by the beginning of 2013. Republicans don't want to take the blame for driving the economy over the cliff.


The current crisis is similar to last year's fight to raise the U.S. debt ceiling, which led to the downgrade of the United States' top credit rating in early August 2011.


During the dealings, the S&P 500 lost 18.8 percent between its peak in July 2011 and its bottom in August. As the market slid, the political standoff badly hurt investors' confidence in Washington, setting off a spike in volatility.


In the end a deal was announced that raised the ceiling and put off longer-term fiscal decisions until January 1, 2013, setting the stage for today's "fiscal cliff" crisis.


After staying flat through September 2011, the S&P 500 jumped 31 percent between its October low and the end of March.


BUY THE DIP?


Gridlock in Washington and all that could possibly go wrong with the economy if a deal is not reached have grabbed the headlines, but the negotiations leave room for stock market gains. Congressional leaders said Friday they will work through the Thanksgiving holiday recess to find a solution.


"The debate over how to solve (the fiscal cliff) may be more productive than is commonly recognized," said Brad Lipsig, senior portfolio manager at UBS Financial Services in New York.


"The U.S. is facing a major debt overhang, and serious steps toward addressing it might ultimately be viewed as a positive for future growth," he said. "The market may recognize this and, after a time of hand wringing, recover from the concerns with a renewed sense of optimism."


The recent selling took the S&P 500's relative strength index - a technical measure of internal strength - below 30 this week, indicating the benchmark is oversold and due for a rebound.


The RSI in four of the 10 S&P sectors - utilities, telecoms, consumer staples and technology - is below 30 and the highest RSI reading, for the consumer discretionary sector, is below 40, suggesting a bounce is in store.


"What I want to do is what we did during the decline following the budget negotiations in the summer of 2011: The lower the stock market goes, the more I want to own stock," said Brian Reynolds, chief market strategist at New York-based Rosenblatt Securities.


"If we go off the cliff it will be with a bungee cord attached," he said.


KEEP CALM AND HEDGE


Volatility is expected to rise through the end of November and to spike in late December if no agreement on the fiscal cliff is reached in Congress. Alongside comes opportunity for those with high risk tolerance.


"Recently, volatility has increased in the market overall. You can't really pick it up in the VIX yet, but I think as we get through November, I think you're likely to see the VIX be at a relatively higher level," said Bruce Zaro, chief technical strategist at Delta Global Asset Management in Boston.


In 2011, the VIX averaged 19.2 in July and 35 in August. So far this month the average is 17.8 and it is expected to spike if negotiations on the cliff drag into late next month.


"Looking at the range of possibilities, I would say any of them would be better than sitting here waiting. I would even put going off the fiscal cliff in that category," said Jill Cuniff, president of Seattle-based Edge Asset Management Inc, which manages about $20 billion.


"But we don't believe Congress will let that happen; there's going to be some middle ground here."


(Reporting by Rodrigo Campos and Jonathan Spincer, additional reporting by Caroline Valetkevitch; Editing by Kenneth Barry)


Read More..

Israeli air strike kills 11 civilians in Gaza: Hamas

GAZA/JERUSALEM (Reuters) - An Israeli missile killed at least 11 Palestinian civilians including four children in Gaza on Sunday, medical officials said, in an apparent attack on a top militant that brought a three-storey home crashing down.


International pressure for a ceasefire seemed certain to mount in response to the deadliest single incident in five days of Palestinian rocket attacks on Israel and Israeli air strikes on the Gaza Strip.


Israel gave off signs of a possible ground invasion of the Hamas-run enclave as the next stage in its offensive, billed as a bid to stop Palestinian rocket fire into the Jewish state. It also spelt out its conditions for a truce.


U.S. President Barack Obama said that while Israel had a right to defend itself against the salvoes, it would be "preferable" to avoid a military thrust into the Gaza Strip, a narrow, densely populated coastal territory. Such an assault would risk high casualties and an international outcry.


A spokesman for the Hamas-run Interior Ministry said 11 people, all of them civilians, were killed when an Israeli missile flattened the home of the Dalu family. Medics said four women and four children were among the dead.


Israel's chief military spokesman said Yihia Abayah, a senior commander of rocket operations in the Gaza Strip, had been the target.


The spokesman, Yoav Mordechai, told Israel's Channel 2 television he did not know whether Abayah was killed, "but the outcome was that there were civilian casualties". He made no direct mention of the destroyed dwelling.


Prime Minister Benjamin Netanyahu said earlier that he had assured world leaders that Israel was doing its utmost to avoid causing civilian casualties in the military showdown with Hamas.


"The massacre of the Dalu family will not pass without punishment," Hamas's armed wing said in a statement.


In other air raids on Sunday, two Gaza City media buildings were hit, witnesses said. Eight journalists were wounded and facilities belonging to Hamas's Al-Aqsa TV as well as Britain's Sky News were damaged.


An employee of the Beirut-based al Quds television station lost his leg in the attack, local medics said.


The Israeli military said the strike targeted a rooftop "transmission antenna used by Hamas to carry out terror activity", and that journalists in the building had effectively been used as human shields by Gaza's rulers.


For their part, Gaza militants launched dozens of rockets into Israel and targeted its commercial capital, Tel Aviv, for a fourth day with one attack in the morning and another after nightfall.


Israel's "Iron Dome" missile shield shot down all three rockets, but falling debris from the daytime interception hit a car, which caught fire. Its driver was not hurt.


In scenes recalling Israel's 2008-2009 winter invasion of Gaza, tanks, artillery and infantry massed in field encampments along the sandy, fenced-off border. Military convoys moved on roads in the area newly closed to civilian traffic.


Netanyahu said Israel was ready to widen its offensive.


"We are exacting a heavy price from Hamas and the terrorist organisations and the Israel Defence Forces are prepared for a significant expansion of the operation," he said at a cabinet meeting, giving no further details.


Gaza health officials said 69 Palestinians - about half of them women and children - have been killed in Gaza since the Israeli offensive began, with hundreds wounded.


The Israeli military said 544 rockets fired from Gaza have hit Israel since Wednesday, killing three civilians and wounding dozens. Some 302 were intercepted and 99 failed to reach Israel and landed inside the Gaza Strip, it added.


Israel's declared goal is to deplete Gaza arsenals and force the Islamist Hamas to stop rocket fire that has bedevilled Israeli border towns for years and is now displaying greater range, putting Tel Aviv and Jerusalem in the crosshairs.


Israel withdrew settlers from Gaza in 2005 and two years later Hamas took control of the impoverished enclave, which the Israelis have kept under blockade.


OBAMA CAUTIONS AGAINST GROUND CAMPAIGN


At a news conference during a visit to the Thai capital Bangkok, Obama said Israel has "every right to expect that it does not have missiles fired into its territory".


He added: "If this can be accomplished without a ramping up of military activity in Gaza that is preferable. That's not just preferable for the people of Gaza, it's also preferable for Israelis because if Israeli troops are in Gaza they're much more at risk of incurring fatalities or being wounded," he said.


Obama said he had been in regular contact with Egyptian and Turkish leaders - to secure their mediation in bringing about a halt to rocket barrages by Hamas and other Islamist militants.


"We're going to have to see what kind of progress we can make in the next 24, 36, 48 hours," he added.


Israeli officials declined to confirm or deny reports that an Israeli negotiator had flown to Cairo to discuss a ceasefire.


Egyptian President Mohamed Mursi said in Cairo, as his security deputies sought to broker a truce with Hamas leaders, that "there are some indications that there is a possibility of a ceasefire soon, but we do not yet have firm guarantees".


Silvan Shalom, one of Netanyahu's deputies, said: "There are contacts, but they are currently far from being concluded."


U.N. Secretary-General Ban Ki-moon will be in Egypt on Monday for talks with Mursi, the foreign ministry in Cairo said. U.N. diplomats earlier said Ban was expected in Israel and Egypt this week to push for an end to the fighting.


Listing Israel's terms for ceasing fire, Moshe Yaalon, another deputy to the prime minister, wrote on Twitter: "If there is quiet in the south and no rockets and missiles are fired at Israel's citizens, nor terrorist attacks engineered from the Gaza Strip, we will not attack."


Israel's operation has so far drawn Western support for what U.S. and European leaders have called its right to self-defence, but there was also a growing number of appeals from them to seek an end to the hostilities.


Read More..