Leah Hostalet Helps Find Kidney Transplant Matches on Facebook

This Valentine's Day, kidney transplant recipient Jerry Wilde is celebrating life with his family thanks to a devoted friend, a generous stranger – and Facebook.

When the kidney he had received through a transplant in 1992 developed a cancerous tumor and was surgically removed, Wilde was put back on dialysis and was told that just eight percent of people with his blood type could be his donor. Dozens of friends, family and colleagues were tested to see if they were a match, but to no avail.

"The waiting period for my blood type on the transplant list was long, between two and a half and three years," says Wilde, 50, a professor of educational psychology at Indiana University East. "I didn't think I'd survive that long. I thought, 'Well this just isn't going to happen. I'm just going to wither away.'"

But when Leah Hostalet, Wilde's friend and former student, saw a status update from Wilde in November of 2011 that he was in search of a kidney donor, she wanted to help.

On November 18 she set up a Facebook page, Find a Kidney for Jerry, which included his blood type and other pertinent medical information. Becky Melton – a total stranger to Wilde – saw the page that would change both their lives.

"I was looking for purpose in my life. It just struck me," says Melton, 28, who was scrolling through Facebook when she saw Jerry's page, "I thought, 'I want to do this. This is my guy. I am going to give him my kidney.' "

Melton, a loan processor in Richmond, Ind., and Wilde exchanged information. On December 14, Melton found out she was a match, and texted Wilde a photo of herself holding a sign with a picture of two kidneys on it. The sign read: "We're a match!" Wilde still gets choked up thinking about that day.

"I was standing in the living room in shock," he says. "I had never met this person. It's like, who does this for a complete stranger?"

On February 24, 2012, the transplant took place and Wilde has been healthy ever since.

From left: Becky Melton, Jerry Wilde and Lea Hostalet four months after his transplant

Courtesy Leah Hostalet

Though thrilled for her friend, Hostalet, a 33 year-old mom of three in Brownsburg, Ind., didn't feel her efforts were done.

"I felt drawn to this cause for some reason, and I felt like there was more I could do," she says.

Her solution? Find a Kidney Central, a hub for kidney donation pages that now is home to 161 people who are in need of a new kidney. In the year the page has been up and running it has linked donors for 38 transplants, and has grown from a bulletin board of information into a vibrant support community for those waiting for transplants.

"Everyone who is in need is so supportive of one another," says Hostalet, "The community feel to the page brings me such joy."

Pairing Kidneys Everywhere

The efforts have created a good will cascade effect: Leona Jones of Bedford, Ind., found and utilized Find a Kidney Central. In July, Jones got a call from her transplant coordinator, who had been contacted by Susan Yost, a woman who had seen Jones's page and wanted to donate her kidney. Though Yost and Jones were not a match, they agreed to participate in a paired donation program at IU Health University Hospital.

They were then connected to Peggy McCormick and her nephew Lucas, who needed a second transplant after his first transplanted kidney started to fail. Peggy donated her kidney to Leona, and Susan was a match for Lucas and donated a kidney to him.

"It was just like everything fit," says McCormick, 58, of donating her kidney to Jones. "It was a match made in heaven."

Doctors told McCormick that it was a miracle that Leona was matched.

"Two days before the transplant we all met," says McCormick. "After we had our preliminary labs done they got us all together in a room. There was a lot of hugging and crying."

Adds Jones, "It was very emotional ... I didn't know these people, and for someone to give up part of their body to you, it's indescribable."

From left: Peggy McCormick, Leona Jones, Susan Yost and Lucas McCormick

Courtesy Peggy McCormick

Hostalet has become a passionate advocate for kidney donation, and spends upwards of 28 hours a week on Facebook helping people set up their own pages and spreading information about her site.

Dr. Bryan Becker, transplant physician and former National Kidney Foundation president, calls Hostalet's work exceedingly important.

"Living kidney donor transplantation is a tremendous way to treat kidney failure with a better likelihood of a good outcome," he says.

Lifelong Bond

As for Wilde and Melton, the two say they share a lifelong bond. Melton is a graduate of IU East, and Wilde had a scholarship named after her, The Becky Melton Scholarship, which is given to a student who exemplifies the spirit of giving.

Hostalet, Melton, Wilde and Wilde's daughter met for dinner one night before the surgery. After dinner, Melton posted the following status on Facebook: "I just met four members of my family that I didn't know."

Hostalet says she is continually inspired by those who post to the site.

"Just seeing their strength, moving forward every day even though they're dealing with this extreme struggle in their lives, it makes me want to keep searching for them. I want to keep educating people as to how difficult dialysis is on the body, and the need for living donors."

As for her next steps, she says, "My plans are to keep this page running and spread as much awareness as possible. I'll take it wherever it leads me. I feel like I'm meant to do this."

Those who are interested in registering as an organ donor on Facebook can do so here.
More Heroes Among Us:

• Scott Neeson Left Hollywood to Save Kids in Cambodia's Slums

• Woman Who Lost her Legs in Tornado Starts Foundation to Help Others

Know a hero? Send suggestions to heroesamongus@peoplemag.com. For more inspiring stories, read the latest issue of PEOPLE magazine

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Study: Fish in drug-tainted water suffer reaction

BOSTON (AP) — What happens to fish that swim in waters tainted by traces of drugs that people take? When it's an anti-anxiety drug, they become hyper, anti-social and aggressive, a study found. They even get the munchies.

It may sound funny, but it could threaten the fish population and upset the delicate dynamics of the marine environment, scientists say.

The findings, published online Thursday in the journal Science, add to the mounting evidence that minuscule amounts of medicines in rivers and streams can alter the biology and behavior of fish and other marine animals.

"I think people are starting to understand that pharmaceuticals are environmental contaminants," said Dana Kolpin, a researcher for the U.S. Geological Survey who is familiar with the study.

Calling their results alarming, the Swedish researchers who did the study suspect the little drugged fish could become easier targets for bigger fish because they are more likely to venture alone into unfamiliar places.

"We know that in a predator-prey relation, increased boldness and activity combined with decreased sociality ... means you're going to be somebody's lunch quite soon," said Gregory Moller, a toxicologist at the University of Idaho and Washington State University. "It removes the natural balance."

Researchers around the world have been taking a close look at the effects of pharmaceuticals in extremely low concentrations, measured in parts per billion. Such drugs have turned up in waterways in Europe, the U.S. and elsewhere over the past decade.

They come mostly from humans and farm animals; the drugs pass through their bodies in unmetabolized form. These drug traces are then piped to water treatment plants, which are not designed to remove them from the cleaned water that flows back into streams and rivers.

The Associated Press first reported in 2008 that the drinking water of at least 51 million Americans carries low concentrations of many common drugs. The findings were based on questionnaires sent to water utilities, which reported the presence of antibiotics, sedatives, sex hormones and other drugs.

The news reports led to congressional hearings and legislation, more water testing and more public disclosure. To this day, though, there are no mandatory U.S. limits on pharmaceuticals in waterways.

The research team at Sweden's Umea University used minute concentrations of 2 parts per billion of the anti-anxiety drug oxazepam, similar to concentrations found in real waters. The drug belongs to a widely used class of medicines known as benzodiazepines that includes Valium and Librium.

The team put young wild European perch into an aquarium, exposed them to these highly diluted drugs and then carefully measured feeding, schooling, movement and hiding behavior. They found that drug-exposed fish moved more, fed more aggressively, hid less and tended to school less than unexposed fish. On average, the drugged fish were more than twice as active as the others, researcher Micael Jonsson said. The effects were more pronounced at higher drug concentrations.

"Our first thought is, this is like a person diagnosed with ADHD," said Jonsson, referring to attention deficit-hyperactivity disorder. "They become asocial and more active than they should be."

Tomas Brodin, another member of the research team, called the drug's environmental impact a global problem. "We find these concentrations or close to them all over the world, and it's quite possible or even probable that these behavioral effects are taking place as we speak," he said Thursday in Boston at the annual meeting of the American Association for the Advancement of Science.

Most previous research on trace drugs and marine life has focused on biological changes, such as male fish that take on female characteristics. However, a 2009 study found that tiny concentrations of antidepressants made fathead minnows more vulnerable to predators.

It is not clear exactly how long-term drug exposure, beyond the seven days in this study, would affect real fish in real rivers and streams. The Swedish researchers argue that the drug-induced changes could jeopardize populations of this sport and commercial fish, which lives in both fresh and brackish water.

Water toxins specialist Anne McElroy of Stony Brook University in New York agreed: "These lower chronic exposures that may alter things like animals' mating behavior or its ability to catch food or its ability to avoid being eaten — over time, that could really affect a population."

Another possibility, the researchers said, is that more aggressive feeding by the perch on zooplankton could reduce the numbers of these tiny creatures. Since zooplankton feed on algae, a drop in their numbers could allow algae to grow unchecked. That, in turn, could choke other marine life.

The Swedish team said it is highly unlikely people would be harmed by eating such drug-exposed fish. Jonsson said a person would have to eat 4 tons of perch to consume the equivalent of a single pill.

Researchers said more work is needed to develop better ways of removing drugs from water at treatment plants. They also said unused drugs should be brought to take-back programs where they exist, instead of being flushed down the toilet. And they called on pharmaceutical companies to work on "greener" drugs that degrade more easily.

Sandoz, one of three companies approved to sell oxazepam in the U.S., "shares society's desire to protect the environment and takes steps to minimize the environmental impact of its products over their life cycle," spokeswoman Julie Masow said in an emailed statement. She provided no details.

___

Online:

Overview of the drug: http://www.nlm.nih.gov/medlineplus/druginfo/meds/a682050.html

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Wall Street flat near multi-year highs, M&A helps

NEW YORK (Reuters) - Stocks were little changed on Thursday as investors found few reasons to keep pushing prices higher with major averages near multi-year highs, though a flurry of merger deals kept indexes steady.

Wall Street has rallied lately, with the S&P 500 briefly hitting its highest intraday level since November 2007 in Wednesday's session. Still, there are few obvious catalysts to continue the rally, and while the S&P is on track for its third straight day of gains, none of those daily gains was more than 0.2 percent.

Shares of H.J. Heinz Co jumped 20 percent to $72.40 after it said Warren Buffett's Berkshire Hathaway and 3G Capital will buy the food company for $72.50 a share, or $28 billion including debt. Berkshire's class B shares rose 1.3 percent to $99.22.

Also supporting the market was data showing the number of Americans filing new claims for unemployment benefits fell more than expected in the latest week. The CBOE Volatility index <.vix> fell 1.4 percent, dropping to 12.8.

"While I'm not bearish, I don't see many upside motivations at these levels," said Donald Selkin, chief market strategist at National Securities in New York, who cited the low level of the VIX as a sign the market was overbought.

"We need to digest some of our gains to go higher, but people are so eager to buy on the dips that we're not even seeing dips anymore. People are just chasing the market higher."

Equities have struggled to break above their current levels, where they have been hovering for almost two weeks. The S&P 500 is up more than 6 percent so far this year.

Stocks fell earlier after a report the euro zone's gross domestic product contracted by the steepest amount since the first quarter of 2009. In addition, Japan's GDP shrank 0.1 percent in the fourth quarter, crushing expectations of a modest return to growth.

The Dow Jones industrial average <.dji> was down 10.21 points, or 0.07 percent, at 13,972.70. The Standard & Poor's 500 Index <.spx> was up 1.21 points, or 0.08 percent, at 1,521.54. The Nasdaq Composite Index <.ixic> was up 1.12 points, or 0.03 percent, at 3,197.99.

Constellation Brands soared more than 38 percent to $43.93 after AB InBev's deal to take over Mexican brewer Grupo Modelo was revised to grant Constellation perpetual rights to distribute Corona and other Modelo brands in the United States. U.S. shares of AB InBev gained 5.1 percent to $92.72.

American Airlines and US Airways Group said they plan to merge in a deal that will form the world's biggest air carrier, with an equity valuation of about $11 billion. US Airways shares fell 9.1 percent to $13.32.

Weakness in Europe contributed to a 5 percent drop in revenue from the region for Cisco Systems , which nonetheless beat estimates as it reported its results late Wednesday. The company's shares slid 1.3 percent to $20.87.

General Motors Co reported a weaker-than-expected fourth-quarter profit, also citing bigger losses in Europe alongside lower prices in its core North American market. The stock was off 2.8 percent at $27.88.

(Editing by Nick Zieminski)

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"Blade Runner" Pistorius charged with murdering girlfriend

JOHANNESBURG (Reuters) - South African "Blade Runner" Oscar Pistorius, a double amputee who became one of the biggest names in world athletics, was charged on Thursday with shooting dead his girlfriend at his upscale home in Pretoria.

Police said they opened a murder case after a 30-year-old woman was found dead at the Paralympic and Olympic star's house in the Silverlakes gated complex on the capital's outskirts.

Pistorius, 26, and his girlfriend, model Reeva Steenkamp, had been the only people in the house at the time of the shooting, police brigadier Denise Beukes told reporters, adding witnesses had been interviewed about the early morning incident.

"We are talking about neighbors and people that heard things earlier in the evening and when the shooting took place," Beukes said outside the heavily guarded residential complex.

Police said a 9mm pistol had been found at the scene.

Beukes said police were aware of previous incidents at the Pistorius house. "I can confirm that there has previously been incidents at the home of Mr Oscar Pistorious, of allegations of a domestic nature," she said.

Pistorius, who uses carbon fiber prosthetic blades to run, is due to appear in a Pretoria court on Friday.

"He is doing well but very emotional," his lawyer Kenny Oldwage told SABC TV, but gave no further comment.

A sports icon for triumphing over disability to compete with able-bodied athletes at the Olympics, his sponsorship deals, including one with sports apparel group Nike, are thought to be worth $2 million a year.

South Africa's M-Net cable TV channel said it was pulling adverts featuring Pistorius off air immediately after blanket coverage of the arrest in a country more used to honoring Pistorius as a national hero.

"WE ARE ALL DEVASTATED"

Steenkamp's colleagues in the modeling world were distraught. "We are all devastated. Her family is in shock," her agent, Sarita Tomlinson, tearfully told Reuters. "They did have a good relationship. Nobody actually knows what happened."

Pistorius, who was born without a fibula in both legs, was the first double amputee to run in the Olympics and reached the 400-metre semi-finals in London 2012.

In last year's Paralympics he suffered his first loss over 200 meters in nine years. After the race he questioned the legitimacy of Brazilian winner Alan Oliveira's prosthetic blades, though he was quick to express regret for the comments.

South Africa has some of the world's highest rates of violent crime, and many home owners have weapons to defend themselves against intruders, although Pistorius's complex is surrounded by a three-meter high wall and electric fence.

In 2004, Springbok rugby player Rudi Visagie shot dead his 19-year-old daughter after he mistakenly thought she was a robber trying to steal his car in the middle of the night.

Before the murder charge was announced, Johannesburg's Talk Radio 702 said the athlete may have mistaken Steenkamp for a burglar.

Pistorius was arrested in 2009 for assault after slamming a door on a woman and spent a night in police custody. Family and friends said it was just an accident and charges were dropped.

OLYMPIAN UNDERGOES POLICE TESTS

Steenkamp, a regular on the South African social scene, was reported to have been dating Pistorius for several months.

In the social pages of last weekend's Sunday Independent she described him as having "impeccable" taste. "His gifts are always thoughtful," she was quoted as saying.

Some of her last Twitter postings indicated she was looking forward to Valentine's Day on Thursday. "What do you have up your sleeve for your love tomorrow???" she posted.

Pistorius was on Thursday being processed through the police system. "At this stage he is on his way to a district surgeon for medical examination," the police brigadier said.

"When a person has been accused of a crime like murder they look at things like testing under the finger nails, taking a blood alcohol sample and all kinds of other test that are done. They are standard medical tests," Beukes said.

Pistorius is also sponsored by British telecoms firm BT, sunglasses maker Oakley and French designer Thierry Mugler.

"We are shocked by this terrible, tragic news. We await the outcome of the South African police investigation," a BT spokeswoman said before Pistorius was charged.

A Nike spokesman in London said before hearing of the murder charge that the company was "saddened by the news, but we have no further comment to make at this stage".

Pistorius also has a sponsorship deal with Icelandic prosthetics manufacturer Ossur.

"I can only say that our thoughts and prayers are with Oscar and the families involved in the tragedy," Ossur CEO Jon Sigurdsson told Reuters. "It is completely premature to discuss or speculate on our business relationship with him."

Neighbors expressed shock at the arrest of a "good guy".

"It is difficult to imagine an intruder entering this community, but we live in a country where intruders can get in wherever they want to," said one Silverlakes resident, who did not want to be named.

"Oscar is a good guy, an upstanding neighbor, and if he is innocent I feel for this guy deeply," he said.

(Additional reporting by Sherilee Lakmidas, David Dolan, Ed Cropley, Jon Herskovitz, Keith Weir and Kate Holton; Writing by Ed Cropley; Editing by Will Waterman)

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Broadcasters blame zombie hack on easy passwords

(Reuters) – Poor password security paved the way for hackers to broadcast a bogus warning on television networks, saying that the United States was under attack by zombies, broadcasters said.

Cyber security experts said the equipment the hackers broke into remained vulnerable to further breaches, and that hackers could potentially take control of the equipment to prevent the government from sending out public warnings during an emergency.

Following the attacks Monday on a handful of TV stations, the government ordered broadcasters to change the passwords for the equipment that authorities use to instantly transmit emergency broadcasts through what is known as the Emergency Alert System, or EAS.

The Federal Communications Commission (FCC) would not comment on the attacks, but in an urgent advisory sent to TV stations on Tuesday, the agency said: “All EAS participants are required to take immediate action.”

It instructed them to change passwords on equipment from all manufacturers used to deliver emergency broadcasts to TV networks, interrupting regular programming. The FCC instructed them to ensure that gear was properly secured behind firewalls and to inspect their systems to ensure that hackers had not queued “unauthorized alerts” for future transmission.

VULNERABLE

The attacks come in the wake of warnings by officials and outside security experts that the United States is at risk of a cyber attack that could cause major physical damage or even cost lives. President Barack Obama has told Congress that some hackers were looking for ways to attack the U.S. power grid, banks and air traffic control systems.

While the zombie hoax appeared to be somewhat innocuous, the relatively easy incursion showed that hackers might be able to wreak havoc with more alarming communications.

“It isn’t what they said. It is the fact that they got into the system. They could have caused some real damage,” said Karole White, president of the Michigan Association of Broadcasters.

White and her counterpart in Montana, Greg MacDonald, said they believed the hackers were able to get in because TV stations had not changed the default passwords they used when the equipment was first shipped from the manufacturer.

But Mike Davis, a hardware security expert with a firm known as IOActive Labs, said hackers could still get past new passwords to remotely access the systems.

Davis said he had submitted a report to the Department of Homeland Security’s U.S. Computer Emergency Readiness Team, or US-CERT, about a month ago that detailed the security flaws.

“Changing passwords is insufficient to prevent unauthorized remote login. There are still multiple undisclosed authentication bypasses,” he told Reuters via email. “I would recommend disconnecting them from the network until a fix is available.”

Davis said he was able to use Google Inc’s search engine to identify some 30 systems that he believed were vulnerable to attack as of Wednesday morning.

A spokesman for US-CERT said he could not immediately comment on the matter.

MANY WAYS IN

Stuart McClure, chief executive of cyber security firm Cylance Inc., said he had investigated cases in which hackers accessed EAS systems via a different method: breaking into hidden accounts built into the systems by manufacturers so that service technicians can easily access them for repairs.

“You cannot give a separate pass code to everybody. Nobody is going to remember it. You have to share the secret,” said McClure, who previously ran a unit at Intel Corp’s McAfee security division that investigated cyber attacks.

He declined to discuss the cases he had worked on, saying that would violate client confidentiality.

Broadcasters and security experts warned that attacks on the Emergency Alert System could undermine the government’s ability to communicate with the public in times of crisis.

“While EAS may not control nuclear power or hydroelectric dams or air traffic control, it can be used to cause widespread panic,” McClure said.

Indeed, far worse than broadcasting zombie jokes, hackers who are able to gain control of the equipment could prevent authorities from warning the public about actual emergencies, McClure added.

Federal Emergency Management Agency spokesman Dan Watson said that the “zombie” breach did not have any impact on the government’s ability to activate the Emergency Alert System.

‘BODIES ARE RISING’

The “zombie” hackers targeted two stations in Michigan, and several in California, Montana and New Mexico, White said.

A male voice addressed viewers in a video posted on the Internet of the bogus warning broadcast from KRTV, a CBS affiliate based in Great Falls, Montana: “Civil authorities in your area have reported that the bodies of the dead are rising from the grave and attacking the living.”

The voice warned not “to approach or apprehend these bodies as they are extremely dangerous.”

Bill Robertson, vice president of privately held electronics manufacturer Monroe Electronics of Lyndonville, New York, told Reuters that equipment from his company had been compromised in at least some of the attacks after hackers gained access to default passwords.

Monroe publishes the default passwords for its equipment in user manuals that can be accessed on its public website.

Robertson said that he believed attackers had been able to access the devices over the Internet because television stations had not properly secured the equipment behind fire walls, which is what Monroe recommends.

“The devices were not really locked down right. They were exposed,” he said.

He said that the company was working to beef up security on the equipment and might update its software to compel customers to change default passwords.

(Editing by Lisa Shumaker, Patrick Graham and Bernadette Baum)

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Jeff Probst Wants an All-Celebrity Season of Survivor

TV Watch

Survivor

By Steve Helling

02/13/2013 at 03:30 PM EST

Neil Patrick Harris (left) and Jeff Probst

Getty; CBS

Will Neil Patrick Harris soon be scheming his way to a Survivor victory?

It could happen. Host Jeff Probst has spoken to the How I Met Your Mother star about playing the game – and is currently looking for other celebrities who want to outwit, outplay and outlast the competition in hopes of being Sole Survivor on the long-running CBS reality show.

A celebrity season actually isn't that far fetched. Last season, The Facts of Life star Lisa Whelchel made the final three. And, in 2001, Kate Hudson and then–husband Chris Robinson showed up for an open audition for Survivor: Australia, before being turned away by producers. (How awesome would that have been?)

But for now, there's Survivor: Caramoan, the show's 26th season, premiering Wednesday night (8 p.m. ET). Ten new players will compete against ten returning players – with early favorites that include Dawn Meehan, a surprisingly tough 42-year-old mother of six from Utah, and Andrea Boehlke, a pretty blonde schemer from Wisconsin.

Catching up with PEOPLE, Jeff Probst reveals what to expect this season – and how a celebrity version would work:

Lisa Whelchel got a lot of buzz last season. Are there any other celebrities you'd like to see play the game?
Mark Burnett and I really want to do a celebrity version. We were just talking about this at a Grammy party last week. Neil Patrick Harris was there, and he told me flat out he wants to play. I challenged him and said "Do you really want to do it, or is this just a fun fantasy that will never happen?" He said, "I want to do it."

So, on the heels of NPH having the guts to say, "I'm in" – I'm putting out the challenge! If you are a celebrity and truly believe you could hack it, it's time to put up. It would be a shortened shoot – maybe 10 days or so – so you can still get back to do your movies and TV shows, and you won't lose so much weight that your agents will panic. But rest assured it will still kick your ass. If we can get a truly great cast together I think CBS would go for it.

Sounds fantastic. But until that happens, there's Survivor Caramoan: Fans vs. Favorites. What can we expect?
Even for Survivor, this is quite an unpredictable season. Evacuations, an impromptu tribal council, emotional breakdowns and a great finish. Of the 26 seasons we've done, I believe this will rank among the most memorable. I also think a couple of new favorites may be born this season.

You've chosen 10 returning contestants to play again – including some surprising choices. Why them?
When deciding on returning players we first look at their popularity. It doesn't mean they have to be well liked, but they must be memorable for something. Then we look at their "story." Is there an expectation surrounding their return – i.e., did Phillip learn anything from playing with Boston Rob? Will Cochran finally stand up and be heard? Will Brandon be able to control his emotions? Can Malcolm finish what he started? With this group we felt each has a story worth telling.

The fans seem awfully young. (Four of the five female fans are under 25.) Do they even stand a chance?
We have a fairly young group of fans, but they know the game well and many have been itching to play for a long time. The question is, will their adoration of the favorites make them vulnerable to a blindside? Or will their enthusiasm be the energy they need to keep up? Favorites have a major advantage going into day one.

Last season, contestant Sarah Dawson caught you by surprise when she kissed you – twice! Have you hired bodyguards to guard your personal space?
It's funny how many people have asked me if I was offended by the kisses. I wasn't at all. The kiss that happened at tribal council was probably due to the delirium brought on by not eating for so long. The kiss at the live reunion show was a funny button at the end of a great season of Survivor. The best part was looking out in the audience to see my wife Lisa laughing hysterically.

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Clues to why most survived China melamine scandal

WASHINGTON (AP) — Scientists wondering why some children and not others survived one of China's worst food safety scandals have uncovered a suspect: germs that live in the gut.

In 2008, at least six babies died and 300,000 became sick after being fed infant formula that had been deliberately and illegally tainted with the industrial chemical melamine. There were some lingering puzzles: How did it cause kidney failure, and why wasn't everyone equally at risk?

A team of researchers from the U.S. and China re-examined those questions in a series of studies in rats. In findings released Wednesday, they reported that certain intestinal bacteria play a crucial role in how the body handles melamine.

The intestines of all mammals teem with different species of bacteria that perform different jobs. To see if one of those activities involves processing melamine, researchers from the University of North Carolina at Greensboro and Shanghai Jiao Tong University gave lab rats antibiotics to kill off some of the germs — and then fed them melamine.

The antibiotic-treated rats excreted twice as much of the melamine as rats that didn't get antibiotics, and they experienced fewer kidney stones and other damage.

A closer look identified why: A particular intestinal germ — named Klebsiella terrigena — was metabolizing melamine to create a more toxic byproduct, the team reported in the journal Science Translational Medicine.

Previous studies have estimated that fewer than 1 percent of healthy people harbor that bacteria species. A similar fraction of melamine-exposed children in China got sick, the researchers wrote. But proving that link would require studying stool samples preserved from affected children, they cautioned.

Still, the research is pretty strong, said microbiologist Jack Gilbert of the University of Chicago and Argonne National Laboratory, who wasn't involved in the new study.

More importantly, "this paper adds to a growing body of evidence which suggests that microbes in the body play a significant role in our response to toxicity and in our health in general," Gilbert said.

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Wall Street rally stalls, S&P 500 skims November 2007 high

NEW YORK (Reuters) - Stocks were little changed on Wednesday amid investor caution after the S&P 500 index briefly hit its highest intraday level since November 2007.

The benchmark index got a boost from Comcast Corp , which said it will buy the rest of NBC Universal for $16.7 billion from General Electric Co .

Equities have been strong performers until recently, buoyed largely by healthy growth in corporate earnings, which helped the S&P 500 to rise 6.5 percent so far this year. The Dow industrials are about 1 percent away from an all-time intraday high, reached in October 2007.

Those gains have left the market vulnerable to a pullback as investors are likely to take profit amid a dearth of new catalysts. While analysts see an upward bias in stocks, recent daily moves have been small and trading volumes light with indexes at multi-year highs.

"I was expecting a 12-15 percent return on the S&P for the whole year of 2013, and we have done about half of that in just 5-6 weeks," said Jack De Gan, principal at Harbor Advisory in Portsmouth, New Hampshire.

"We will hit resistance, but the fundamentals and (microeconomic) picture are looking good, so if there is a correction, it's going to be a brief one."

The Dow Jones industrial average <.dji> was down 39.17 points, or 0.28 percent, at 13,979.53. The Standard & Poor's 500 Index <.spx> was up 0.80 points, or 0.05 percent, at 1,520.23. The Nasdaq Composite Index <.ixic> was up 7.01 points, or 0.22 percent, at 3,193.50.

Investors shrugged off the latest economic data, which showed that retail sales rose just 0.1 percent, as expected, in January as tax increases and higher gasoline prices restrained spending.

The S&P 500 was well above its 50-day moving average of 1,460.92, a sign the market could be overbought.

Comcast agreed late Tuesday to buy General Electric Co's remaining 49 percent stake in NBC Universal for $16.7 billion. Comcast jumped 4.4 percent to $40.70 as the S&P's top percentage gainer while Dow component GE was up 3.3 percent to $23.33.

Deere & Co reported earnings that beat expectations and raised its full-year profit outlook. After initially rallying in premarket trading, the stock fell 3 percent to $91.13.

According to the latest Thomson Reuters data, of the 353 companies in the S&P 500 that have reported results, 70.3 percent have exceeded analysts' expectations, above a 62 percent average since 1994 and 65 percent over the past four quarters.

Fourth-quarter earnings for S&P 500 companies are estimated to have risen 5.3 percent, according to the data, above a 1.9 percent forecast at the start of the earnings season.

Industrial and construction shares fell, though President Barack Obama, in his State of the Union address late Tuesday, called for $50 billion in spending to create jobs by rebuilding degraded roads and bridges.

The Dow Jones Home Construction index <.djushb> was off 0.5 percent.

(Editing by Kenneth Barry and Bernadette Baum)

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Ovation for Pope Benedict at final public mass

VATICAN CITY (Reuters) - A capacity crowd in St Peter's Basilica gave Pope Benedict a thunderous standing ovation on Wednesday at an emotional last public Mass before he resigns at the end of the month.

"Thank you. Now, let's return to prayer," the 85-year-old pontiff said, bringing an end to several minutes of applause that clearly moved him. In an unusual gesture, bishops took off their mitres in a sign of respect and a few of them wept.

One of the priests at the altar, which according to tradition rests above the tomb of St Peter, took out a handkerchief to dry his tears.

The Mass was moved to St Peter's from a venue in Rome so more people could attend. Hundreds of others waited outside.

Hours earlier in the Vatican's modern audience hall, a visibly moved Benedict tried to assure his worldwide flock, saying he was confident his decision to step down would not hurt the Church.

The Vatican, meanwhile, announced that a conclave to elect his successor would start sometime between March 15 and March 20, in keeping with Church rules about the timing of such gatherings after the papal see becomes vacant.

"Continue to pray for me, for the Church and for the future pope," he said in unscripted remarks at the start of his weekly general audience, his first public appearance since his shock decision on Monday that he will step down on February 28.

It was the first time Benedict, 85, who will retire to a convent inside the Vatican, exchanging the splendor of his 16th century Apostolic Palace for a sober modern residence, had uttered the words "future pope" in public.

Church officials are still so stunned by the move that the Vatican experts have yet to decide what his title will be and whether he will continue to wear the white of a pope, the red of a cardinal or the black of an ordinary priest.

His voice sounded strong at the audience but he was clearly moved and his eyes appeared to be watering as he reacted to the thunderous applause in the Vatican's vast audience hall, packed with more than 8,000 people.

In brief remarks in Italian that mirrored those he read in Latin to stunned cardinals on Monday he appeared to try to calm Catholics' fears of the unknown.

He message was that God would continue to guide the Church.

EXAMINATION OF CONSCIENCE

"I took this decision in full freedom for the good of the Church after praying for a long time and examining my conscience before God," he said.

He said he was "well aware of the gravity of such an act," but also aware that he no longer had the strength required to run the 1.2 billion member Roman Catholic Church, which has been beset by a string of scandals both in Rome and round the world.

Benedict said he was sustained by the "certainty that the Church belongs to Christ, who will never stop guiding it and caring for it" and suggested that the faithful should also feel comforted by this.

He said that he had "felt almost physically" the affection and kindness he had received since he announced the decision.

When Benedict resigned on Monday, the Vatican spokesman said the pontiff did not fear schism in the Church after his resignation.

Some 115 cardinals under the age of 80 will be eligible to enter a secret conclave to elect his successor.

Cardinals around the world have already begun informal consultations by phone and email to construct a profile of the man they think would be best suited to lead the Church in a period of continuing crisis.

The conservative Benedict has appointed more than half of the cardinals who will elect his successor so it is unlikely the new man will tamper with any teachings such as the ban on artificial birth control or women priests.

But many in the Church have been calling for the election of someone who they say will be a better listener to other opinions in the Church.

The likelihood that the next pope would be a younger man and perhaps a non-Italian, was increasing, particularly because of the many mishaps caused by Benedict's mostly Italian top aides.

Benedict has been faulted for putting too much power in the hands of his friend, Secretary of State Cardinal Tarcisio Bertone. Critics of Bertone, effectively the Vatican's chief administrator, said he should have prevented some papal mishaps and bureaucratic blunders.

ILL-SERVED POPE

"These scandals, these miscommunications, in many cases were caused by Pope Benedict's own top aides and I think a lot of Catholics around the world think that he was perhaps ill-served by some of the cardinals here," said John Thavis, author of a new book, The Vatican Diaries.

Benedict's papacy was rocked by crises over sex abuse of children by priests in Europe and the United States, most of which preceded his time in office but came to light during it.

His reign also saw Muslim anger after he compared Islam with violence. Jews were upset over rehabilitation of a Holocaust denier. During a scandal over the Church's business dealings, his butler was accused of leaking his private papers.

"When cardinals arrive here for the conclave ... they are going to have this on their mind, they're going to take a good hard look at how Pope Benedict was served, and I think many of them feel that the burden of the papacy that finally weighed so heavy on Benedict was caused in part by some of this in-fighting (among his administration)," Thavis told Reuters.

Vatican spokesman Father Federico Lombardi urged the faithful to remain confident in the Church and its future.

"Those who may feel a bit disorientated or stunned by this, or have a hard time understanding the Holy Father's decision should look at it in the context of faith and the certainty that Christ will support his Church," Lombardi said.

Lombardi said that on his last day in office, Benedict would receive cardinals in a farewell meeting and after February 28 his ring of office, used to seal official documents, would be destroyed just as if he had died.

(Reporting by Philip Pullella; Editing by Giles Elgood)

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Employee Facebook privacy bill advances in Colo.

DENVER (AP) — Facebook profiles and other social-media accounts could be off-limits to employers under a bill approved unanimously in a Colorado House committee Tuesday.

The measure, approved 11-0, would bar most employers from requiring access to their workers’ personal accounts. Several states already have such protections, and dozens more are considering them.

The bill would not prohibit companies from looking at Facebook pages or punishing employees for what they post on their personal sites. But it would ban them from requiring current or potential employees to provide passwords for personal accounts.

The measure’s sponsor said private social media accounts should be considered like physical photographs.

“It’s never been acceptable for en employer to ask to see an employee’s personal photos,” said Rep. Angela Williams, D-Denver.

The bill was amended to exempt law enforcement agencies and corrections workers, since those workers’ personal opinions or off-duty actions can affect their use as witnesses in criminal matters.

“They need to know that the people they have working for them are above reproach and have a higher standard,” said Ann Marie Jensen of the Colorado Association of Chiefs of Police.

Lawmakers rejected a proposal to give all businesses permission to require personal social media access for “legitimate business interests.”

Kim Smiley of the Colorado Defense Lawyers Association suggested businesses should be allowed to require access in some cases. She used examples of an employee threatening violence or bragging about drinking alcohol on the clock.

Lawmakers responded that employers dealt with those problems long before social media networking. Rep. Libby Szabo, R-Arvada, pointed out that employers once used their noses to suss out an employee who drank too much at lunch.

“There was life before Facebook,” Szabo said.

The measure awaits one more committee vote before it’s considered by the full House.

___

House Bill 1046: http://bit.ly/UOffsH

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